Cours international

5th Course "Development and Cancer: From Pigment Cell Developement to Melanomas" - 2016

The course presents the current knowledge in neural crest and melanocytes development (cell biology, transcriptomics, imaging...), as well as how melanocytes undergo tumor progression in adults. It ends with presentation of the most up-to-date therapeutical strategies.

In humans, pigment cells comprise the neural crest-derived melanocytes and the pigmented retina cells. Tumor transformation in both cell types results in cutaneous or uveal melanomas, two usually aggressive and hard-to-treat tumour types. This course will address the development, the differentiation and the migratory behaviour of melanocytes in embryos and melanoma formation and metastasis in adults. Focus will be made on cellular and molecular mechanisms controlling these processes. The course will then address how advanced imaging technologies, systems biology, and in vivo approaches have progressed in melanoma understanding in the last few years. Finally, some directions for therapeutic approaches will be developped.
In the practical part of this course, the notions developped in the seminars and courses will be illustrated by in vivo manipulations in embryos and in vitro cellular manipulation, both followed by advanced imaging analysis.

Organizers: A-H. Monsoro-Burq, S. Saule, P. Pla, C. Borday, L. Méry, F. Coquelle

Master 2 students, graduate students and postdoctoral fellows with a scientific background are invited to apply to the course. Researchers are welcome as well. Seminars and talks will be in English. The practical course is open to Paris-Sud students and students registered in another French university.

Online registration only (free of charge but compulsory).

January 11-15, 2016
10 January 2016

Institut Curie Research Center, Paris Sud University, University Center, 91405 Orsay, France.

No registration fees are requested.

Anne Hélène Monsoro-Burq, (Institut Curie et Université Paris Sud),
Simon Saule (Institut Curie et Université Paris Sud),
Patrick Pla (Institut Curie et Université Paris Sud),
Caroline Borday (Institut Curie et Université Paris Sud).
Frederic Coquelle (Université Paris Sud).
Laurence Méry (Institut Curie et Université Paris Sud)

To discuss the big questions in the field of Development and Cancer. To provide an up-to-date landscape on melanocyte biology, for master and doctoral students as well as for researchers.

Pigment cell development: signals, differentiation and migration,
Cell migrations in vivo, in embryos and cancer,
Cutaneous and uveal melanomas,
Medulloblastoma biology,
High throughput technologies and imaging for tumor analysis,
Melanoma and therapies.

Career Development: from academic research to private research.

Joint Institut Curie – Paris-Sud University Course.
ECTS will be issued by Paris Sud University: for Paris Sud students or students from other French universities with a suitable agreement with Paris Sud University (fee). The attendance to the practical course is limited to 12 students. Doctoral students wil be able to validate these seminars for their graduate program in agreement with their doctoral school of origin. Attendance certificates will be issued for all participants. For details, please contact the organizers.