International multidisciplinary courses
This course focuses on breast cancers both on a biological and a clinical point of view. It will cover the biology of breast cancers from stem cell biology to metastatic process encompassing special courses on diagnostic of the disease, the state -of art of treatment with presentation of clinical trials and modalities of follow-up. A special focus will emphasize the recent data on oestrogen resistance, basal-like and hereditary breast cancers, their new therapeutic strategies and what next generation sequencing provides in breast cancer biology and clinical management.
Organizers: Roman Rouzier, Anne Vincent-Salomon and Jean-Yves Pierga
This career Development workshop is a unique opportunity for participants, PhD students and young postdocs, to discuss their career objectives with speakers who, after earning a PhD in biology, chose various career paths leading them away from the bench (education, industry, science communication and management, etc…). The workshop is organized in short round-tables, where participants and invited speakers will exchange in an informal way.
Each participant should have the opportunity to discuss with at least 7 speakers.
The 9th Edition of the Cytoskeleton course will be divided in two parts:
1st part (form Wednesday to Saturday) will follow the spirit of the cytoskeleton course in the previous years: during the day we will have local speakers that will give 1h talks mixed of text book information and on-going research in their labs. In the evenings the students will present their work in 10-15 min in closed environment. On Saturday, there will be career development workshop.
2nd part (from Monday to Wednesday), will follow the spirit of the Labex CelTisPhyBio course: international invited speakers will give 1-2h research seminar talks. In addition, there will be a number of short talks selected from abstracts. Other participants will present posters.
Organizers: S. Miserey-Lenkei, G. Montagnac, D. Vignjevic
The third session of the LABEX DCBIOL course will focus on « Anti-tumor Immunotherapy ». Immunotherapy is about to revolutionize cancer treatment. It consists in treating cancer by stimulating the immune system so it can efficiently attack tumor cells. The aim of this course is a better understanding of how the immune system actors including dendritic cells detect and fight tumor cells and how their activities can be boosted. It will include talks on the clinical applications of immunotherapy in cancer treatments.
Internationally renowned scientists expert in the field will give talks. This course is totally free and open to all the members of the DCBIOL Labex community (Institut Curie, Paris and CIML, Marseille) and to scientists working in the field (subscription of young scientists will be privileged).
Organizers: Evelina Gatti, Sandrine Henri, Claire Hivroz, Manal Sarkis
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The Paris Alliance for Cancer Research Institutes (PACRI), an alliance of Institut Curie, Gustave Roussy Cancer Campus, Institut St. Louis and University Paris Descartes has the pleasure to announce a two-day conference in Paris on 23 and 24 March 2017.
The « Future of Oncology » will gather 20 renowned speakers who will address the main topics and the major challenges of fundamental and translational cancer research in the next years.
Do not miss this great scientific event, register now!
The aim of this course is to provide an overview of post-transcriptional gene regulations at multiple steps, including notably (pre-)messenger RNA splicing, polyadenylation, stability and translation, this year with a focus on two emerging topics, mRNA localization and modifications (epitranscriptome).
In addition to lectures given by international experts in the field, the course will also rely on the active contribution of participants and on their interactions with speakers. Each participant will present his scientific project (poster, elevator pitch) and will co-chair a speaker. In addition to long discussion time after each talk, participants will have the opportunity to meet speakers every day at coffee breaks and lunch.
The aim of this course is to provide an overview of epigenetic mechanisms and their link to chromatin dynamics. The different functions of the nucleus involving the genome and its organization will be discussed with an emphasis on technological limits and the new experimental approaches being developed today. Links between the disruption of nuclear functions and the development of human pathologies will be discussed.
The success of the course relies on the active contribution of participants who are expected to be proactive and to participate in all of the events organized including:
i) presentation of their own scientific project with a poster
ii) participation in the Journal Club to both present and review key articles proposed by the speakers,
iii) participation to the "career development" workshop during the Saturday morning and the "epi-Courses" such as the “Art & Science” workshop.
A special session will be devoted to 2 or 3 alumni who have gone on to successful careers in the field of Epigenetics.
Organizers: Geneviève Almouzni, Nathalie Dostatni
In humans, pigment cells comprise the neural crest-derived melanocytes and the pigmented retina cells. Tumor transformation in both cell types results in cutaneous or uveal melanomas, two usually aggressive and hard-to-treat tumour types.
This course will address the development, the differentiation and the migratory behaviour of melanocytes in embryos and melanoma formation and metastasis in adults. Focus will be made on cellular and molecular mechanisms controlling these processes. The course will then address how advanced imaging technologies, systems biology, and in vivo approaches have progressed in melanoma understanding in the last few years. Finally, some directions for therapeutic approaches will be developped.
In the practical part of this course, the notions developped in the seminars and courses will be illustrated by in vivo manipulations in embryos and in vitro cellular manipulation, both followed by advanced imaging analysis. An opening will be made on other cancers that have similarities with melanoma as medulloblastoma and glioblastoma.
This course will explore the versatility of non-coding RNAs, a diverse and prevailing class of transcripts that engage in numerous biological processes across every branch of life in all living organisms from bacteria to humans. Word-famous researches will expose their very last discoveries in identification and biogenesis to functional roles of non-coding RNAs in physiology and human disease. It will provide an opportunity to young students and research fellows to discuss their work with an international scientific community in a warm and stimulating environment of Institut Curie.
Organizers: D. Bourc'his, Ines Drinnenberg, E. Heard, A. Londono, A. Morillon, M. Pinskaya, A. Shkumatava, F. Toledo
One of the fundamental issues in biology is the understanding of the relationship between the multiple spatial and temporal scales observed in a biological system. From molecules to a cellular function, from a collection of cells to an organism, or from individuals to a population, the complex interactions between singular elements can give rise to “emergent” properties at the ensemble level. To what extent can the spatial and temporal order seen at the system level be explained by subscale properties?
During this course, most seminars were filmed. Discover videos here.
Organizers: M. Coppey, M. Dahan, H. Isambert, P. Martin, P. Nghe, P. Sens, P. Silberzan, A. Walczak