Cours international

1er Cours : Biologie des Systèmes du Cancer - 2018

The objective of the course is to promote integration of computational approaches into biological and clinical labs. We aim to help participants to improve interpretation and use of omics and imaging data that nowadays are accumulated in any biological or medical lab.

Systems biology approaches help to analyse molecular mechanisms in silico. Despite availability of cancer high-throughput (omics) and imaging data, they are not fully exploited to provide the clue on deregulated mechanisms that would guide to better patient’s stratification and to specific treatment in cancer and beyond.

We invited leading international speakers from different fields in cancer systems biology that will expose an umbrella of systems biology methods from data analysis to modelling and integration of rationalized treatment schemes into the clinical trials. 

The course will contain the following sessions:

Session 1: Pathway databases and networks resources in cancer
Session 2: Visualisation and interpretation of cancer data
Session 3: Cancer genomics
Session 4: Multi-level omics data analysis and tumour heterogeneity 
Session 5: Mathematical modelling of signalling networks in cancer
Session 6: integration of multi-level data into models of cancer signalling
Session 7: Treatment response prediction and patient stratification
Session 8: Single cell data analysis in cancer
Session 9: Bioimage informatics for cancer research 
Session 10: Cancer evolution studies

The success of the course relies on the active contribution of participants who are expected to participate in the following events:

-Presentation of their own scientific project with a flash presentation and a poster
-Participation in the Journal Club to present and discuss milestone papers in the cancer systems biology field
-Participation in the "career development" workshop during the Saturday morning session.

CRC Taylor&Francis Publishing Group sponsored student’s prizes for best presentations and posters. 

Organizers: E.BARILLOT, G.BATT, I.KUPERSTEIN, V.SOUMELIS, D.THIEFFRY, J-P.VERT, T.WALTER 

The course can accommodate 60-80 Master, PhD students and post-doctorants from:
-French universities/teams (10-15 places)
-European universities/teams (10 places)
-International universities/teams (10 places)

This course extends over 5.5 days and can be validated by 4 ECTS for Master 2 students by UPMC (10-15 places) and IBENS-ENS (10 places).

The course will be taught in English.

In addition, we expect free attendees among researchers and medical doctors that interested to learn about systems biology impact into cancer research and treatment.

No previous experience in programming and modelling methods or deep knowledge in systems biology is required. The talks will be constructed in a didactic manner, introducing the audience to the basics on systems biology approaches and applications for cancer research.

Selections are based on applications.
All successful applicants are requested to present a flash presentation and a poster on their scientific research. Most significate abstract will be chosen for 15 minutes talks.

Application should include:
-CV (max. 1 page)
-Description of scientific topic in a form of abstract (max. 1 page)
- Motivation letter explaining objectives to attend the course (max. 1 page)
-1-2 reference contacts (for Master and PhD students only)

Scientific papers within the main topics covered by the course will be sent to the accepted applicants for presentations during the journal club.

24-29 septembre, 2018
25 Juillet 2018

Institut Curie, BDD building, Amphithéâtre BDD
11 Rue Pierre et Marie Curie, 75248 Paris cedex 05
Paris - France

5 août, 2018

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Organisateurs
Emmauel BARILLOT Institut Curie - INSERM U900, Paris, France
Gregory BATT Inria - Saclay - Institut Pasteur, Paris, France
Inna KUPERSTEIN Institut Curie - INSERM U900, Paris, France
Vassili SOUMELIS Institut Curie - INSERM U932, Paris, France
Denis THIEFFRY Institut de Biologie de l'École Normale Supérieure, Paris, France
Jean-Philippe VERT Centre of Computational Biology, MINES - ParisTech, Paris, France
Thomas‎ WALTER Centre of Computational Biology, MINES - ParisTech, Paris, France

Comité Scientifique
Laurence CALZONE Institut Curie – INSERM U900, Paris, France
Tatiana POPOVA Institut Curie – INSERM U830, Paris, France
Andrei ZINOVYEV Institut Curie – INSERM U900, Paris, France

Career development workshop (half a day on Saturday)
Introduction to career development opportunities in computational systems biology of cancer. Presentation of career paths and assistance of students by (round tables):
-Invited speakers
-Pharma representatives

UPMC, Institut Pasteur, IBENS-ENS, MINES-PariTech

Servier
Sanofi
CNRS GDR-BIM
LABEX DC-BIOL
CRC Taylor&Francis Publishing Group